Synthetic Chemist

YOUR ROLE

As a Synthetic Chemist (Scientist I) at Enveda, you'll build Enveda's library of synthetic authentic standards: human metabolites made quickly and at scale, so our mass spec platform can confirm what it finds. You'll partner with analytical chemists, data scientists, and our Sample Management and Lab Automation teams to turn computationally predicted structures into confirmed compounds. In your first year, you'll stand up our high-throughput synthesis workflow and deliver 250,000 confirmed authentic standards across multiple compound classes. This is a high impact opportunity where you'll influence our mass spec platform and Enveda's compound collection strategy while collaborating with some of the brightest minds in the industry.

Own and design syntheses for our authentic standard library, from target list to confirmed compound, including efficient routes to structurally diverse natural metabolites and underexplored compound classes, designed so each compound can be confidently confirmed by LC-MS Develop and scale parallel or mixture synthesis workflows that enable rapid production of metabolite authentic standards for analytical validation Build the infrastructure and processes to maximize compound production, partnering with our Sample Management and Lab Automation teams on high-throughput experimentation and automation Translate computationally predicted molecular structures into confirmed, fully characterized compounds, closing the loop between data science and wet-lab chemistry, fast enough that synthesis is never the bottleneck Establish best practices for synthesis prioritization, route scouting, and library design so the team can move quickly through large numbers of targets Work in tight feedback loops with analytical chemists and data scientists who are predicting novel metabolite structures from mass spectrometry data at scale Support the metabolomics teams who rely on synthetic standards to validate discoveries, and the drug discovery teams who build on the metabolites your standards help confirm Help shape Enveda's compound collection strategy, deciding which regions of chemical space to explore next and how to build a library with lasting scientific value

We hire for trajectory, not just credentials. If you meet most of the above and care deeply about this problem, we want to hear from you. 

ABOUT ENVEDA

We're a clinical-stage, AI-enabled biotech discovering medicines from nature four times faster than the industry standard. We recently raised $311M in a Series E, bringing total funding to over $845M, and doubled our valuation to $2B. We now have three oral medicines in the clinic, including our lead drug, ENV-294, in Phase 2 trials for eczema and asthma. Forbes named us one of America's Best Startup Employers, and Newsweek recognized us as a Top 100 Most Loved Workplace. We're still early, and most of the best work is ahead of us.

Benefits (Starting Day 1): Medical, dental, and vision covered at 90%, 401(k) with company match, flexible PTO and a company-wide weeklong recharge break, adoption assistance

Our Process: We move fast and respect your time. Typically: a recruiter screen → hiring manager conversation → work sample, technical interview, & culture interview.

Our Values: Curiosity | Agency | Journey | Charity | Unity

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